Navigator

Choosing a Strategy

Navigator ships four optimizer strategies, selected by the strategy field in your target config.

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The optimizer ships four strategies, selected by the strategy field in your target config (navigator roster lists them):

PresetRole
alpha_diversity_screeningDefault. Broad global discovery — start here.
gamma_diversity_screeningFaster/balanced alternative screen.
beta_diversity_screeningAdvanced exploration (experimental).
analog_harvestHarvest analogs of your best chemotypes (beta).

Run alpha_diversity_screening first; once you have measured hits, switch to analog harvesting over the same archive and budget:

navigator transition --run-dir runs/hk --to analog_harvest
navigator propose    --run-dir runs/hk

analog_harvest reports how concentrated its hits are on every proposal and warns if a campaign narrows to one or two chemotype families.

Honesty note

analog_harvest has the strongest single-run hit-count result on record, but it strongly concentrates into a few chemotypes — it is a harvesting policy, not a validated replacement for global discovery. beta_diversity_screening is experimental.

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